Volume 39: Issue 1

Introduction

While the controversy over compounding for animals is contemporary, the practice of compounding for animals is not. Pharmaceutical compounding is an ancient art and science. Compounding has been an integral part of the practice of veterinary medicine since the first cures were blended together to help an animal patient. Skilled healers have utilized compounds for both human and animal patients for thousands of years.

With hundreds of species requiring treatment and dozens of new diseases emerging, the half-life of truth in veterinary medicine is particularly short. As a result of a complex and lengthy approval

This report describes the antemortem diagnosis and antemortem and postmortem findings of superficial necrolytic dermatitis with hepatopathy (i.e., hepatocutaneous syndrome) in a cat. A 5-year-old Maine coon was evaluated because of a history of pruritic alopecia and liver enzyme elevations. Abdominal ultrasonography revealed a reticular pattern to the hepatic parenchyma. Histopathological findings of the liver were nodular regeneration with bands of vacuolated hepatocytes and bile duct hyperplasia, characteristic of the hepatopathy frequently associated with superficial necrolytic dermatitis. Skin histopathology revealed multifocal parakeratosis, midepidermal spongiosis, and basal cell hyperplasia consistent with superficial necrolytic dermatitis.

This study determined the extent and duration of cutaneous acidification caused by a single application of four acidifying sprays, vinegar, and water. Multivariate repeated measures analysis of variance revealed a significant difference between the six sprays (F=15.3; P≤0.001). Linear contrast tests showed that the effects of the acidifying sprays were significantly different from vinegar and water (F=6.0; P≤0.001), and vinegar was significantly different from water (F=13.8; P≤0.001). The acidifying sprays decreased cutaneous pH to <6.0 for a mean range of 50 to 65 hours, while vinegar did so for a mean of 12 hours.

Traumatic body wall hernias (TBWH) are serious sequelae to traumatic injury in dogs and cats. During the study period, 26 dogs and 10 cats with surgically managed TBWH were identified. Five cases (four dogs, one cat) did not have their hernias identified during the first 24 hours of hospitalization. Bite wounds were the most common cause of TBWH, accounting for 54% of canine and 40% of feline hernias. Twelve cases (nine dogs, three cats) had serious intra-abdominal injuries diagnosed in addition to their TBWH. Seventy-three percent of dogs and 80% of cats survived to hospital discharge. In addition, the authors report the occurrence of a unique cause of herniation, termed an autopenetrating hernia.

Severe Neurological Signs and Hypernatremia Secondary to Polyethylene Glycol Paintball Ingestion in a Dog

Bruce GravesDVM,

Jessica KielbDVM, DACVECC, and

Nolan ChalifouxDVM, MSTR, DACVECC

The Compounding Controversy: What Veterinarians Should Know to Protect Themselves and Their Patients

Introduction

Transdermal Therapeutics

Clinicopathological, Ultrasonographic, and Histopathological Findings of Superficial Necrolytic Dermatitis With Hepatopathy in a Cat

The Effects of Four Acidifying Sprays, Vinegar, and Water on Canine Cutaneous pH Levels

Traumatic Body Wall Herniation in 36 Dogs and Cats

Gastric Outflow Obstruction After Ingestion of Wood Glue in a Dog

Prevalence of Enteric Pathogens in Dogs of North-Central Colorado

Ultrasonographic Signs of Intestinal Intussusception Associated With Acute Enteritis or Gastroenteritis in 19 Young Dogs

Juvenile Hyperthyroidism in a Cat

Clinicopathological Evidence of Pseudomyxoma Peritonei in a Dog With Intestinal Mucinous Adenocarcinoma

Treatment of Renal Nephroblastoma in an Adult Dog

Extradural Spinal, Bone Marrow, and Renal Nephroblastoma

Efficacy of Cobalt-60 Radiation Therapy for the Treatment of Nasal Cavity Nonkeratinizing Squamous Cell Carcinoma in the Dog

Intravascular Lymphoma Involving the Central and Peripheral Nervous Systems in a Dog

Distraction Osteogenesis for Treatment of Premature Physeal Closure and Shortening of the Third and Fourth Metatarsals of a Dog

Table of Contents

Severe Neurological Signs and Hypernatremia Secondary to Polyethylene Glycol Paintball Ingestion in a Dog

The Effect of Time of Antimicrobial Administration on the Outcome of Septic Dogs

Hyperechoic Retroperitoneal Fat in a Cat with Systemic Coagulopathy

Myocarditis in a Dog Positive for Brucella canis

A Retrospective Study on Boar-Induced Trauma in 42 Dogs

Soft-Tissue Sarcomas in Dogs: A Review

Vascular Encephalopathy Associated With Bacterial Endocarditis in Four Dogs

The Use of Carbon Dioxide Laser for the Ablation of Meibomian Gland Adenomas in Dogs

Outcomes of Dogs Presented for Cataract Evaluation: A Retrospective Study

Nutritional Myths